• hdchem@ou.ac.lk
  • +94 112 881 371
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Department of
CHEMISTRY

Dr. P. R. Haputhanthri

B.Sc (University of Peradeniya); MSc in Chemistry, Mississippi State University, Mississippi, USA; PhD in Chemistry (Monash University, Victoria, Australia)

Senior Lecturer (G II)

Department of Chemistry
  • Colombo Regional Center, Department of Chemistry, Faculty of Natural Sciences, The Open University of Sri Lanka, Nawala
  • prhap@ou.ac.lk

I earned my Ph. D. (with Prof. Donald McNaughton, Prof. Bayden R Wood and Emeritus Prof. Glen Deacon. on A Spectroscopic investigation into the interaction of novel Platinum (IV) and Platinum (II) anticancer drugs with DNA and cells” in 2017 from the Monash University, Melbourne, Australia. From October 2017 to March 2022, I was a Research Fellow at the Sri Lanka Institute of Nanotechnology where I carried out research work in the areas of nanoencapsulation, and client- based analytical chemistry.

I joined The Open University of Sri Lanka as a Senior Lecturer in Chemistry (2022-April-up to date). I have authored about 1 chemistry book name SERS of Thiobarbituric Acid (TBA) and TBA Reactive Compounds: Surface-Enhanced Raman Spectroscopy (SERS)

 I involved in publishing over 6 Scientific Papers in International refereed Journals with 198 citations and I have presented about in 3 Conferences.

Spectroscopy/Synchrotron Spectroscopy
Multivariate Analysis
Computational Chemistry
Cell Culture
Biomedical Imaging
Nanotechnology
Platinum Anticancer Drugs

Biomedical Imaging, Spectroscopy, Multivariate Analysis, Computational Chemistry, Nanotechnology

Professional Record

  • Senior Lecturer Department of Chemistry Faculty of Natural Sciences, The Open University of Sri Lanka, 2022 – Present
  • Research Fellow, Sri Lanka Institute of Nanotechnology (SLINTEC) 2017-2022
  • Senior Lecturer SLINTEC Academy 2018-2020
  • Demonstrator, Research Assistant Monash University, Australia 2013- 2017
  • Internship, École Polytechnique Fédérale de Lausanne, Switzerland 2014 Oct-2014 Dec
  • Teaching Assistant, Institute of Chemistry Ceylon, Sri Lanka 2012-2013
  • Teaching Assistant/ Research Assistant, Department of Chemistry, Mississippi State University, USA, 2008-2011
  • Chemist, Dreamron (Pvt.) Ltd, Sri Lanka (Cosmetic Industry) 2006-2008
  • Vocational Industrial Research Training, Dipped Product Ltd, Sri Lanka 07/2006–10/2006


CYU 3302 Basic Practical Chemistry
CYU 6304 Inorganic Spectroscopy and Structural Chemistry
LLU 3261 Introduction to the laws of Sri Lanka

Research interests:

  • Biomedical Imaging
  • Spectroscopy
  • Multivariate Analysis
  • Computational Chemistry
  • Nanotechnology


Books

Haputhanthri P. R. SERS of thiobarbituric acid (TBA) and TBA reactive compounds. Lambert Academic Publishing, Germany. (ISBN 978-3-659-10646-0), 2012.

 

  • Haputhanthri R., Sandaruwan C., Peries C. Preparation, characterization and slow-release study of encapsulated cinnamon essential oil Microencapsul. 2022 (Submitted)
  • Perera, K.D.C; Weragoda, G. K; Haputhanthri, R; Rodrigo, S. K; Study of concentration dependent curcumin interaction with serum biomolecules using ATR-FTIR spectroscopy combined with Principal Component Analysis (PCA) and Partial Least Square Regression (PLS-R). Vib. Spectrosc. 2021, 116, 1-9 (IF-2.35).
  • Al-Jorani, K; Ruther, A.; Martin M.; Haputhanthri, R.; Deacon, G. B.; Li, H..; Wood, B. R.; The application of ATR-F, TIR Spectroscopy and the Reversible DNA conformation as a sensor to test the effectiveness of Platinum (II) anticancer drugs. Sensors, 2018, DOI: 10.3390/s18124297. (IF – 3.275)
  • Al-Jorani, K; Ruther, A.; Haputhanthri, R.; Deacon, G. B.; Li, H.; Cullinane, C.; Wood, B. R.; ATR-FTIR Spectroscopy shows changes in ovarian cancer cells after incubation with novel organoamidoplatinum complexes. Analyst, 2018, DOI: 10.1039/x0xx00000x (IF -3.978)
  • Haputhanthri, R.; Ojha, R.; Izgorodina, E. I.;Guo, S-X.; Deacon, G. B.; McNaughton, D.; Wood, B. R.;  A Spectroscopic investigation into the binding of novel platinum(IV) and platinum(II) anticancer drugs with DNA. Vib. Spectrosc. 2017,  92, 82–95. (IF-2.35)
  • Ansar, S. M.; Haputhanthri, R.; Edmonds, B.; Liu, D.; Yu, L.; Sygula, A.; Zhang, D. Determination of the binding affinity, packing, and conformation of thiolate and thione ligands on gold. J. Phys. Chem. C 2011, 115, 653-660. (IF-4.189)
  • Zhang, D.; Haputhanthri, R.; Ansar, S.; Vangala, K.; De Silva, H.; Sygula, A.; Saebo, S.; Pittman, C. Ultrasensitive detection of thiobarbituric acid reactive compounds with surface-enhanced Raman spectroscopy. Anal. Bioanal. Chem. 2010, 398, 3193-3201. (IF-3.74)


Conference Presentations

  • S.Pituwalakankanamge, R.N.wijesena, N.D.Tissera, R. Haputhanthri and K.M. N De Silva  “Insight of silver chitin nanoparticle interaction” TIKM, (2018)
  • Rukshani Haputhanthri; Glen B Deacon; Ruchika Ojha; Donald McNaughton; Ewelina W. Lipiec; Bayden R. Wood; “Vibrational spectroscopic investigation into the binding of platinum complexes with DNA” ACOVS 10, (2014)
  • Pravindya Haputhanthri; “Dongmao Zhang. “Drastic pH and concentration dependent surface-enhanced Raman spectra of thiobarbituric acid.” SERMACS Meeting, (2010)

 

Poster Presentations

  • Rukshani Haputhanthri; Glen B Deacon; Ruchika Ojha; Donald McNaughton; Ewelina W. Lipiec; Bayden R. Wood; “Vibrational spectroscopic investigation into the binding of platinum complexes with DNA” ACOVS 10, (2015) (First place)
  • Pravindya Haputhanthri; Dongmao Zhang. “Ultrasensitive detection of thiobarbituric acid reactive compounds using surface-enhanced Raman spectroscopy.”FACSS Meeting, (2009). (Third Place)

 

  • Poster Presentation, Australian Conference on Vibrational Spectroscopy (ACOVS 10), 2015 First place
  • Dean’s International Postgraduate Research Scholarship (DIPRS) 2013, Monash University, Australia
  • Poster Presentation, Federation of Analytical Chemistry and Spectroscopy (FACSS) meeting 2009, Third Place
  • Graduate Teaching Assistantship 2008, Mississippi State University, USA


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