Dr P. R. Haputhanthri

Senior Lecturer


Department of Chemistry
Faculty of Natural Sciences
GS
Senior Lecturer
Contact:

Colombo Regional Center, Department of Chemistry, Faculty of Natural Sciences, The Open University of Sri Lanka, Nawala

Office: , Ext:

E-mail: prhap@ou.ac.lk


Academic Record

  • PhD in Chemistry, Monash University, Victoria, Australia 2013-2017

Dissertation: “A Spectroscopic investigation into the interaction of novel Platinum (IV) and Platinum (II) anticancer drugs with DNA and cells” (Advisor: Prof. Donald McNaughton, Prof. Bayden Wood, Emeritus Prof. Glen Deacon)

  • MSc in Chemistry, Mississippi State University, Mississippi, USA 2008-2011

Dissertation: “Surface-enhanced Raman Spectroscopy of Thiobarbituric Acid (TBA) and TBA Reactive Compounds” (Advisor: Prof. Dongmao Zhang Prof Svein Saebo)

  • BSc, Chemistry (Honors), University of Peradeniya, Sri Lanka 2002-2006

Honours project: “Removal of Zinc ions from aqueous medium using feldspar” (Advisor: Prof. Namal Heenkenda)

 

Professional Record

  • Senior Lecturer Department of Chemistry Faculty of Natural Sciences, The Open University of Sri Lanka, 2022 – Present
  • Research Fellow, Sri Lanka Institute of Nanotechnology (SLINTEC) 2017-2022
  • Senior Lecturer SLINTEC Academy 2018-2020
  • Demonstrator, Research Assistant Monash University, Australia 2013- 2017
  • Internship, École Polytechnique Fédérale de Lausanne, Switzerland 2014 Oct-2014 Dec
  • Teaching Assistant, Institute of Chemistry Ceylon, Sri Lanka 2012-2013
  • Teaching Assistant/ Research Assistant, Department of Chemistry, Mississippi State University, USA, 2008-2011
  • Chemist, Dreamron (Pvt.) Ltd, Sri Lanka (Cosmetic Industry) 2006-2008
  • Vocational Industrial Research Training, Dipped Product Ltd, Sri Lanka 07/2006–10/2006

Last Updated on 2 years

Areas of Specialization:

Analytical and Physical Chemistry

  • Spectroscopy/Synchrotron Spectroscopy
  • Multivariate Analysis
  • Computational Chemistry
  • Cell Culture
  • Biomedical Imaging
  • Nanotechnology
  • Platinum Anticancer Drugs
Research interests:
  • Biomedical Imaging
  • Spectroscopy
  • Multivariate Analysis
  • Computational Chemistry
  • Nanotechnology
Course Coordination:
  • CYU 3302 Basic Practical Chemistry
  • CYU 6304 Inorganic Spectroscopy and Structural Chemistry
  • LLU 3261 Introduction to the laws of Sri Lanka
Awards:
  • Poster Presentation, Australian Conference on Vibrational Spectroscopy (ACOVS 10), 2015 First place
  • Dean’s International Postgraduate Research Scholarship (DIPRS) 2013, Monash University, Australia
  • Poster Presentation, Federation of Analytical Chemistry and Spectroscopy (FACSS) meeting 2009, Third Place
  • Graduate Teaching Assistantship 2008, Mississippi State University, USA
Publications:

Books

  • Haputhanthri P. R. SERS of thiobarbituric acid (TBA) and TBA reactive compounds. Lambert Academic Publishing, Germany. (ISBN 978-3-659-10646-0), 2012.

Journal Articles

  • Haputhanthri R., Sandaruwan C., Peries C. Preparation, characterization and slow-release study of encapsulated cinnamon essential oil Microencapsul. 2022 (Submitted)
  • Perera, K.D.C; Weragoda, G. K; Haputhanthri, R; Rodrigo, S. K; Study of concentration dependent curcumin interaction with serum biomolecules using ATR-FTIR spectroscopy combined with Principal Component Analysis (PCA) and Partial Least Square Regression (PLS-R). Vib. Spectrosc. 2021, 116, 1-9 (IF-2.35).
  • Al-Jorani, K; Ruther, A.; Martin M.; Haputhanthri, R.; Deacon, G. B.; Li, H..; Wood, B. R.; The application of ATR-F, TIR Spectroscopy and the Reversible DNA conformation as a sensor to test the effectiveness of Platinum (II) anticancer drugs. Sensors, 2018, DOI: 10.3390/s18124297. (IF – 3.275)
  • Al-Jorani, K; Ruther, A.; Haputhanthri, R.; Deacon, G. B.; Li, H.; Cullinane, C.; Wood, B. R.; ATR-FTIR Spectroscopy shows changes in ovarian cancer cells after incubation with novel organoamidoplatinum complexes. Analyst, 2018, DOI: 10.1039/x0xx00000x (IF -3.978)
  • Haputhanthri, R.; Ojha, R.; Izgorodina, E. I.;Guo, S-X.; Deacon, G. B.; McNaughton, D.; Wood, B. R.;  A Spectroscopic investigation into the binding of novel platinum(IV) and platinum(II) anticancer drugs with DNA. Vib. Spectrosc. 2017,  92, 82–95. (IF-2.35)
  • Ansar, S. M.; Haputhanthri, R.; Edmonds, B.; Liu, D.; Yu, L.; Sygula, A.; Zhang, D. Determination of the binding affinity, packing, and conformation of thiolate and thione ligands on gold. J. Phys. Chem. C 2011, 115, 653-660. (IF-4.189)
  • Zhang, D.; Haputhanthri, R.; Ansar, S.; Vangala, K.; De Silva, H.; Sygula, A.; Saebo, S.; Pittman, C. Ultrasensitive detection of thiobarbituric acid reactive compounds with surface-enhanced Raman spectroscopy. Anal. Bioanal. Chem. 2010, 398, 3193-3201. (IF-3.74)

Conference Presentations

  • S.Pituwalakankanamge, R.N.wijesena, N.D.Tissera, R. Haputhanthri and K.M. N De Silva  “Insight of silver chitin nanoparticle interaction” TIKM, (2018)
  • Rukshani Haputhanthri; Glen B Deacon; Ruchika Ojha; Donald McNaughton; Ewelina W. Lipiec; Bayden R. Wood; “Vibrational spectroscopic investigation into the binding of platinum complexes with DNA” ACOVS 10, (2014)
  • Pravindya Haputhanthri; “Dongmao Zhang. “Drastic pH and concentration dependent surface-enhanced Raman spectra of thiobarbituric acid.” SERMACS Meeting, (2010)

Poster Presentations

  • Rukshani Haputhanthri; Glen B Deacon; Ruchika Ojha; Donald McNaughton; Ewelina W. Lipiec; Bayden R. Wood; “Vibrational spectroscopic investigation into the binding of platinum complexes with DNA” ACOVS 10, (2015) (First place)
  • Pravindya Haputhanthri; Dongmao Zhang. “Ultrasensitive detection of thiobarbituric acid reactive compounds using surface-enhanced Raman spectroscopy.”FACSS Meeting, (2009). (Third Place)
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