Research-Physics Dept

Research Grant No: Faculty Research Grant 2019 (Grant no: OUSL/ FHS/19/01)

Title of the Ongoing Research Project:

Screening and Detection of Biofilm Production in Clinical Bacterial Isolates from Indwelling Urinary Catheters

Principal Investigator: Dr. Kalaivani Vivehananthan

Co- Investigators: Dr. Indrika Abeygunawardena
Ms Sajantha Thevashayinath

Description:

Biofilm is a cluster of microbial cells that is irreversibly adhered with biotic and abiotic surfaces. These microbial organisms are embedded in a matrix of extracellular polymeric substances that they have produced. Indwelling medical devices are more prone to get colonization of bacteria on their intra and extra luminal surfaces. Especially indwelling urinary catheters which are used by patients to drain urine are known to be the major common site of biofilm producing bacteria. Biofilms have serious medical importance as they increase the resistance to the antimicrobial drugs. The present study is designed to isolate bacteria and detect their biofilm production in vitro. The results of this study could be disseminated to the health care sectors.

1. Dassanayaka, M.P., Vivehananthan, K. and Hettiarachchi, G.H.C.M. (2018). Isolation and Screening of Three Phenol Degrading Pseudomonas spp from Different Waste Environments in Sri Lanka. Open University International Research Sessions iOURS 2018. pp 99.
2. Rajapaksha R.W.P.M., Dennis Mac Nevin and Vivehananthan K. (2018).16S rDNA Metagenomic analysis of bacterial diversity associated with seed potato imported into Sri Lanka for cultivation. Poster presentation, Australian Bioinformatics and Computational Society Conference, ABACBS University of Melbourne, Australia. pp
3. Rajapaksha R.W.P.M., Vivehananthan K., Warshamana I.K. (2018). Next Generation Sequencing for the Detection of Quarantine Important Microbial Pathogens in Imported Seed Potato. Proceedings of South Asian Biotechnology Conference 2018 (SABC), pp70
4. MP Dassanayaka, K Vivehananthan and GHCM Hettiarachchi (2018). Isolation of two phenol biodegrading bacteria; Pseudomonas aeruginosa and Alcaligenes faecalis from petroleum contaminated wastewater in Sri Lanka. Abstract. Proceeding of Wayamba University International Conference, Sri Lanka. pp. 106
5. MP Dassanayaka, K Vivehananthan and GHCM Hettiarachchi (2018). Screening of Phenol Catabolic Genes in Bacteria Isolated from Sri Lankan Petroleum Contaminated Site. Abstract. Proceeding of 5th International Conference on Agriculture, pp. 29
6. Dassanayaka MP, Vivehananthan K and Hettiarachchi GHCM (2018). Molecular Confirmation of Phenol degradation by Klebsiella Pneumoniae. Proceeding of Wayamba University Research Congress – 2018. Sri Lanka. pp. 1-2
7. Rajapaksha R.W.P.M., Vivehananthan K., Warshamana I.K. (2018). Quarantine Pathogen Ralstonia solanacearum in Potato Seed Lots Imported to Sri Lanka. Wayamba University Research Congress. pp

8. Madhuranga, W.S.P., Vivehananthan, K. and Dassanayaka, M.P. (2018). Enhanced Biodegradation Efficiency of Phenol by Klebsiella pneumoniae, Stapylococcus warneri, Klebsiella variicola and Ochrobactrum intermedium. Proceeding of 7th YSF (Young Scientist Forum) Symposium, Sri Lanka. pp 82-85.

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