Research-Basic Sciences

Research Grants

Research Grant No: Faculty Research Grant 2020 (Grant no: OUSL/ FHS/20/01)

Title of the Ongoing Research Project: Isolation and Molecular Identification of Endophytic Bacteria from CissusQuadrangularis

Principal Investigator: Dr. KalaivaniVivehananthan

Co- Investigators: Prof.S.Y.Sudhalaksh

 

Research Grant No: Faculty Research Grant 2020 (Grant no: OUSL/ FHS/20/03)

Title of the Ongoing Research Project: Determination of Residual Amoxicillin in selected environmental water bodies using HPLC assisted ZnOCNF  sorption studies and its effect on  bacterial species

Principal Investigator: Dr.O.K.D.U.P.Nishshanka

Co- Investigators: Dr. UdayaJayasundara

 

Research Grant No: Faculty Research Grant 2019 (Grant no: OUSL/ FHS/19/01)

Title of the Ongoing Research Project:Screening and Detection of Biofilm Production in Clinical Bacterial Isolates from Indwelling Urinary Catheters

Principal Investigator: Dr. KalaivaniVivehananthan

Co- Investigators: Dr. IndrikaAbeygunawardena
Ms.SajanthaThevashayinath

Description:

Biofilm is a cluster of microbial cells that is irreversibly adhered with biotic and abiotic surfaces. These microbial organisms are embedded in a matrix of extracellular polymeric substances that they have produced. Indwelling medical devices are more prone to get colonization of bacteria on their intra and extra luminal surfaces. Especially indwelling urinary catheters which are used by patients to drain urine are known to be the major common site of biofilm producing bacteria. Biofilms have serious medical importance as they increase the resistance to the antimicrobial drugs. The present study is designed to isolate bacteria and detect their biofilm production in vitro. The results of this study could be disseminated to the health care sectors.

Journal Articles

  1. Vivehananthan, K., Thevashayinath, S. and Abeygunawardena, I. (2020). The Role of Bacterial Biofilms in Infections and Effective Prevention Strategies for Biofilm Formation in Urinary Catheters. OUSL Journal, 15 (1), pp. 83–99. DOI:  http://doi.org/10.4038/ ouslj. v15i1.7465. .https://ouslj.sljol.info/articles/abstract/10.4038/ouslj.v15i1.7465
  2. Kumari, P.M.S.S., & Wijekoon, P. (2019). Distribution of Butterfly Species Associated with Environmental Factors in Sri Lanka. Asian Journal of Environment & Ecology, 9 (3), 1-18. DOI:  https://doi.org/10.9734/ajee/2019/v9i330093
  3. KJ Duelge, U Nishshanka, HG De Alwis KJ Duelge, U Nishshanka, HG De Alwis (2018). An LC–MS/MS method for the determination of antibiotic residues in distillers grains.  Journal of Chromatography B
  4. Rajapaksha R.W.P.M and Vivehananthan K (2017). Microbial DNA Extraction from infected Seed Potato from Molecular Diagnostic Applications.  International Journal of Advanced Research.  ISBN 2320-5407.  5 (1): 2605-2611
  5. Rajapaksha R.W.P.M, Vivehananthan K, Warshamana I.K (2017). Detection of Quarantine Pathogen Pectobacterium caratovorum in Potato Seed Lots Imported to Sri Lanka. InternationalJournal of Scientific and Research Publications. ISSN 2250-3153. 7 (2): 110-116
  6. Upul Nishshanka, Hiranthi Jayasuriya, Chaitali Chattopadhaya, Philip J Kijak, Pak-Sin Chu, Renate Reimschuessel, Andriy Tkachenko, Olgica Ceric, Hemakanthi G De Alwis (2016). Screening for toxic phorbol esters in jerky pet treat products using LC–MS.  Journal of Chromatography Volume 1020, 1. pp 90-95
  7. Chongming Liu, Upul Nishshanka, Athula B Attygalle (2016). Formation of Carbamate Anions by the Gas-phase Reaction of Anilide Ions with CO2.  Journal of The American Society for Mass Spectrometry
  8. Vivehananthan K, Yamini Sudha Lakshmi S, De SilvaW.H and Kumar S A (2015).  Silver Nanoparticles of Azadirachta indica: Biological Method of Synthesis and Characterization. World Journal of Pharmaceutical Research, 4 (11):  77-86, ISSN 2277– 7105 (SJIF   2014 Impact Factor 5.990 and ICV 5.90) (Article Score rank 86/100)
  9. Vivehananthan K, Kumari AHVV, De Silva WH, Fernando CAN (2015). Synthesis and Evaluation of Antimicrobial Property of Bionanoparticles ISI/Scopus indexed Journal, Research Journal of Applied Sciences, 10 (4):  161-166

 

 

Conference Publications

  1. Thevashayinath S, Vivehananthan, K Abeygunawardena (2020). Detection of Biofilm Production and Biochemical Identification of Biofilm Bacterial Isolates in Indwelling Urinary Catheters, OURS 2020, The Open University of Sri Lanka (accepted).  S Amirthalingam, MP
  2. Kumari, P.M.S.S., & Wijekoon, P (2020). Identifying primary factors that affect the Chronic Kidney Disease (CKD) with a Comparative analysis of Heavy Metals in Drinking Water. International Conference on Environmental and Medical Statistics.
  3. Dassanayaka, K Vivehananthan (2019). Influence and optimization of growth conditions on phenol degradation by Pseudomonas aeruginosa.4thInternational Research Symposium on Pure and Applied Sciences, Faculty of Science, University of Kelaniya, Sri Lanka.
  4. Rajapaksha R.W.P.M., Drapper J., Young J., Linacre A., Mac Nevin D and Vivehananthan K. (2019). A comparison of Three Bioinformatics Pipelines on 16S rDNA Next generation Sequence Analysis for Microbial Diversity Detection of Imported seed Potato. Proceedings of Wayamba University Research Congress, Sri Lanka. pp. 1-2
  5. Kumari, P.M.S.S., Wijekoon, P (2019). An R-Shiny Web Application to Determine the Butterfly Species Interaction and Changing Diversity with Environmental Factors.Association for Tropical Biology and Conservation, ATBC Asia-pacific Chapter Meeting, Sri Lanka
  6. Kumari, P.M.S.S., Wijekoon, P (2019). Butterfly Species Diversity Associated with Environmental Factors in Sri Lanka. Faculty Research Congress (FacSciResCon), 1 (61).
  7. Amirthalingam, S., Dassanayaka, M.P., Balasooriya, B.L.W.K., &Vivehananthan, K. (2018). Optimization of Growth Conditions for Biodegradation of Phenol by Pseudomonas aeruginosa. Proceedings of the17th Agricultural Research Symposium of Wayamba University of Sri Lanka, pp81-85.
  8. Rajapaksha R.W.P.M., Dennis Mac Nevin and Vivehananthan K. (2018).16S rDNA Meta genomic analysis of bacterial diversity associated with seed potato imported into Sri Lanka for cultivation. Poster presentation, ABACBS (Australian Bioinformatics and Biology Computational Society Conference), University of Melbourne.
  9. Dassanayaka,M.P., Vivehananthan, K. and Hettiarachchi, G.H.C.M. (2018). Isolation and Screening of Three Phenol Degrading Pseudomonas spp from Different Waste Environments in Sri Lanka. Open University International Research Sessions(OURS 2018), pp 99
  10. Rajapaksha R.W.P.M., Vivehananthan K., Warshamana I.K. (2018). Next Sequencing for the Detection of Quarantine Important Microbial Pathogens in Imported Seed Potato. Proceedings of South Asian Biotechnology Conference 2018 (SABC), pp70
  11. MP Dassanayaka, K Vivehananthan and GHCM Hettiarachchi (2018). Isolation of two phenol biodegrading bacteria; Pseudomonas aeruginosaand Alcaligenes faecalis from petroleum contaminated wastewater in Sri Lanka. Abstract. Proceeding of Wayamba University International Conference, Sri Lanka. pp. 106
  12. MP Dassanayaka, K Vivehananthan and GHCM Hettiarachchi (2018).  Screening of Phenol Catabolic Genes in Bacteria Isolated from Sri Lankan Petroleum Contaminated Site. Abstract. Proceeding of 5thInternational Conference on Agriculture, pp. 29
  13. Madhuranga, W.S.P., Vivehananthan, K., & Dassanayaka, M.P. (2018). Enhanced Biodegradation Efficiency of Phenol by Klebsiella pneumoniae, Stapylococcus warneri, Klebsiella variicola and Ochrobactrum intermedium. Proceeding of 7thYSF Symposium, pp.82-85
  14. Dassanayaka MP, Vivehananthan K and Hettiarachchi GHCM (2018). Molecular Confirmation of Phenol degradation by Klebsiella Pneumoniae.Proceeding of Wayamba University Research Congress, Sri Lanka. pp. 1-2.
  15. Madhuranga, W.S.P., Vivehananthan, K. and Dassanayaka, M.P. (2018). Enhanced Biodegradation Efficiency of Phenol by Klebsiella pneumoniae, Stapylococcus warneri, Klebsiella variicola and Ochrobactrum intermedium. Proceeding of 7th YSF (Young Scientist Forum) Symposium. Sri Lanka. pp 82-85
  16. M.S.S.Kumari, Supervised by Prof.P.Wijekoon.– BUSA:Butterfly Species Analyzer” Using R, e-Swabhimani (2018) Digital Social Impact Awards in the category Environment & Green Energy. Link: https://shamali.shinyapps.io/shiny-app/
  17. Madhuranga WSP, Vivehananthan K, Dassanayaka MP (2017). Biodegradation of Phenol by Four Selected bacteria Isolated from Sri Lankan Petroleum Contaminated Sites.  Proceedings of the 16th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 16-20
  18. M.I.M. Herath, R.P.V.J. Rajapakse, K. Vivehananthan, (2017). Evaluation of Anti-Cancer Effect and Wound Healing Activity of Ceylon Cinnamon (Cinnamomum zeylanicum).Proceedings of the 16th Agricultural Research Symposium, Wayamba University of Sri Lanka.
  19. M.Warangi, R.P.V.J. Rajapakse, K. Vivehananthan (2017). Evaluation of Cytotoxicity and Wound Healing Properties of Turmeric (Curcuma longa Linn).Proceedings of the 16th Agricultural Research Symposium, Wayamba University of Sri Lanka
  20. Dassanayaka, M.P., Vivehananthan, K. and Hettiarachchi, G.H.C.M (2017). Molecular Identification of Potential Phenol Biodegrading Bacteria by 16 S rRNA Sequence Analysis. Abstract. Proceeding of 12th Malaysia International Genetics Congress. Malaysia. pp. 79
  21. Dassanayaka,M.P., Vivehananthan, K. and Hettiarachchi, G.H.C.M. (2017). Biodegradation of Phenol by Two Proteobacteria: Klebsiella variicola and Ochrobactrum intermedium. Proceeding of 4th International Conference on Agriculture and Forestry. Sri Lanka. pp. 56.
  22. Dassanayaka,M.P., Vivehananthan, K. and Hettiarachchi, G.H.C.M. (2017). Screening of potential phenol biodegrading bacteria from petroleum contaminated wastewater in Colombo, Sri Lanka. Extended Abstract. Proceedings of 3rd Research and Developmental Study Symposium of the National Water Supply and Drainage Board. pp 140 -143.
  23. Dassanayake MP, Vivehananthan K and Hettiarachchi GHCM (2017). Estimation of Phenol Degradation by selected Bacterial Isolated from Contaminated Site in Kolonnawa. Proceedings of 2nd Wayamba University Research Conference, pp 62-63.
  24. Balachandran J, Vivehananthan K and Bandara N and Mannapperuma N (2017). Treatment of Landfill Leachate by using Three Different Extracts of Selected Medicinal Plants.  3rd Research and Development Study Symposium-2017, Symposium Proceedings, World Water Day.  pp 129-133.
  25. Rajapaksha R.W.P.M., Vivehananthan K., Warshamana I.K. (2017). Revealing Latent Infections of Imported Seed Potato by Next Generation Sequencing. Proceedings of Wayamba University Research Congress. pp 52-53
  26. De Silva, KKDS and Silva, RM., An Analysis of Batting Consistency in ODI Cricket Using One-Sided EWMA Control Chart (2017). Proceedings of the International Statistics Conference 2017. IASSL
  27. B.Alahapperuma, K. Vivehananthan, N. Neththi kumara, S.Gnaneshan, V.H.W. Dissanayake and R.W.P.M. Rajapaksha (2016). Development of a Bioinformatics Pipeline and Identification of Plant Pathogens using Next Generation Sequencing (NGS) Data. Proceedings of the 15th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 111-115. ISBN 978-955-4709-37-9
  28. P.D.L. Luphzhy, K. Vivehananthan, M.P. Dassanayaka and D.C.Satharasinghe (2016). Isolation and Characterization of Methicillin Resistant Staphylococcus aureus from Hospital Effluents, Proceedings of the 15th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 120-124. ISBN 978-955-4709-37-9
  29. Balachandran, K. Vivehananthan, N. Bandara and N. Mannapperuma (2016). Improving the Quality of Landfill Leachate by using Plant Leaf Extracts to Control the Odour at Karadiyana Site, Proceedings of the 15th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 154-158. ISBN 978-955-4709-37-9
  30. M.A.Y.Herath, K. Vivehananthan, R.P.V.J. Rajapakse, C. Rathnayakeand D.C. Satharasinghe(2016). Safety Assessment of Neem (Azadirachta indica) Leaf Extracts on BALB/c Mice for Anticancer Therapy, Proceedings of the 15th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 149-153. ISBN 978-955-4709-37-9
  31. H.D. Tharangi, K.Vivehananthan, W.H. De Silva1and C.A.N. Fernando(2016). UV Characterization of Green Synthesis of Silver Nanoparticles and its’ Effects on Phytopathogenic Fungi. Proceedings of the 15th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 140-143. ISBN 978-955-4709-37-9
  32. B. Jayalatharachchi, K. Vivehananthan and W.H. De Silva (2016). Design of Nanofilter for Improving the Quality of Wastewater, Proceedings of the 15th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 169-173. ISBN 978-955-4709-37-9
  33. W.M. Tharindi, W.K. Balasooriya, B. Suganthan and K. Vivehananthan (2016). Isolation and Identification of Culturable Cyanobacteria from Paddy Soils of the Intermediate Zone of Sri Lanka, Proceedings of the 15th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 159-163. ISBN 978-955-4709-37-9
  34. Kumar S.A, Vivehananthan K and DE Silva W.H (2016). Preparation and Optimization of Silver nanoparticles to treat household. 3rd International Conference on Nanoscience and Nanotechnology
  35. Luffzy MPDL, Dassanayake MP, Vivehananthan K (2016). Screening of methicillin resistant gene for identification of potential methicillin resistant Staphylococcus aureus from clinical wastes.  Institute of Biology. Pp
  36. Dassanayake MP, Vivehananthan K and Hettiarachchi GHCM (2016). Optimization of a protocol to isolate bacteria tolerating higher phenol concentrations and identifying their maximum tolerable level. Proceedings of Wayamba International Conference, WinC 2016, Wayamba University of Sri Lanka. pp 237
  37. W.P.M. Rajapaksha, K. Vivehananthan, W.M.J.Y. Ekanayake and Y.W.Manukulasooriya (2016). Molecular Techniques for Identification of Xenobiotic Degrading Bacteria in Waste Environment, Proceedings of the Wayamba University Research Congress, Wayamba University of Sri Lanka. pp 30-31. ISBN 978-955-4709-46-1.
  38. H. De Silva, K. Vivehananthan and S.A. Kumara (2016). Optimization of   Silver Nanoparticles to Upgrade the Quality of Wastewater, Proceedings of the Wayamba University Research Congress, Wayamba University of Sri Lanka. pp 42-43. ISBN 978-955-4709
  39. Vivehananthan K and De Silva.W.H (2016). Nanotechnology:  An Emerging Trend in Wastewater Treatment”.  Proceedings of the 2nd Research and Development Study Symposium, pp 53-57
  40. Fernando KHN, Vivehananthan K and Rajapaksha RWPM (2015). Detection of Quarantine Bacterial Pathogens in Imported Seed Potatoes using Molecular Techniques. Proceedings of the 14th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 155-159, ISBN 978-955-470937-9.
  41. Wickramasinghe TD, Vivehananthan K and Rajapaksha RWPM (2015). An Improved Protocol to extract Microbial DNA to identify Xenobiotic degrading isolates in Environmental Samples.  Proceedings of the 14th Agricultural Research Symposium,    Wayamba University of Sri Lanka. pp 169-173, ISBN 978-955-470937-9.
  42. Kumar S.A, Vivehananthan K and DE Silva W.H (2015). Effects of Silver Nanoparticles on Microbial Load in Different Types of Wastewater.Proceedings of the 14th Agricultural Research Symposium, Wayamba University of Sri Lanka. pp 160-163.  ISBN 978-955-470937-9.
  43. Vivehananthan K (2015). “Advancements on Environmental Biotechnology: A Way Forward to Clean and Green Environment” International Seminar on BiotechnologyChallenging the Challenges of the Changing World; Valedictory Address, pp 118
  44. Upul Nishshanka, Pak-Sin Chu, Eric Evans, Renate Reimschuessel, Nicholas Hasbrouck, Kande Amarasinghe, Hiranthi Jayasuriya (2015). Tentative Structural Assignment of a Glucuronide Metabolite of Methyltestosterone in Tilapia Bile by Liquid Chromatography–Quadrupole-Time-of-Flight Mass Spectrometry.   Food Chem, 63, 24, 5753–5760
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