Professor.(Mrs) R.M.R.P. Ratnayake

Associate Professor in Chemistry

Department of Chemistry
Faculty of Natural Sciences
Associate Professor in Chemistry
Contact:

KRC, 3rd floor, Science and Technology building, Room No : W5

Office: 812494497, Ext:

Email: rurat@ou.ac.lk rukmalratnayake@yahoo.com


Academic Record:

  • Ph.D. in Chemistry, University of Peradeniya, 2002
  • B.Sc. Chemistry Honours, University of Peradeniya, 1992

 

 

 

 

Area of Specialization:
  • Organic Chemistry
  • Natural Product Chemistry
Research Intrests:

Organic Synthesis, Natural Products

Course Coordination:

 

CHU 3130 (Natural Products Chemistry) – 2008 to 2015 

CHU 3131(Chemistry of Sugars, Amino acids and related compounds) -2008 to 2015 

CMU 3120 (Organic Chemistry II) – 2014 

CMU 3124 (Chemistry of Biomolecules) – 2015- Jan 2018 

Awards:

2012 NRC (National Research Council) Merit Award for Scientific Publication 

2008 Presidential Award for Research Publications

2002 Best paper at Annual Research Sessions, University of Peradeniya (Biological Sciences) Some Studies on the Genus Hortonia, (2002) H.E.M.D.K. Ekanayake, R.M.R.P.Ratnayake and N.L.V.V. Karunaratne

2001 Presidential Award for Research Publications

 

 

 

Researches:

1. Two New Lactones with mosquito larvicidal activity from three Hortonia species. Rukmal Ratnayake, Veranja Karunaratne, B.M. Ratnayake Bandara, Vijaya Kumar, Jhon. K. MacLoed and Peta Simmonds, J. Nat. Prod 2001, 64, 376-378.

2. Four butanolide derivatives from Hortonia species, a genus endemic to Sri Lanka. Ratnayake, Rukmal / Bandara, Ratnayake B M / Wijesundara, Siril A D / Carr, Gavin /Andersen, Raymond J / Karunaratne, Veranja, Journal of Chemical Research Part S Synopsis 2008, (3), 134-136.

3  Bioactivity and Chemistry of the genus Hortonia. Rukmal Ratnayake, B.M. Ratnayake Bandara,  Siril Wijesundara, Jhon. K. MacLoed, Peta Simmonds and Veranja Karunaratne, J. Nat. Prod Res. 2008;22(16):1393-402

4. Complete 2-D-assignment and antifungal activity of Ishwarane isolated from the genus Hortonia (2008) R. Ratnayake, S. Jayasinghe, R.J. Anderson and V. Karunaratne, J. National Science Foundation of Sri Lanka, 36 (1), 109-122

5. Hortonones A to C , hydroazulenons from the genus Hortonia.Gavin Carr†, David E. Williams†, Rukmal Ratnayake‡, Ratnayake Bandara‡, Siril Wijesundara§, Tamsin Tarling, Aruna D. Balgi, Michel Roberge, Raymond J. Andersen*†, and Veranja Karunaratne‡ J. Nat. Prod., 2012, 75 (6), pp 1189–1191

6. Evaluation of species limits of Hortonia by DNA barcoding Sanath Rajapakse, Prabasheeni Iddamalgoda, Rukmal Ratnayake, D.S.A. Wijesundara, B.M.Ratnayake Bandara, Veranja Karunaratne J.Natn.Sci.Foundation Sri Lanka 2012 40 (4): 345-349

7. Antioxidant activity  and a new butanolide from the primitive endemic genus Hortonia. Rukmal Ratnayake, Damith Perera, D. Nedra Karunaratne,D. Siril A. Wijesundara,Gavin Carr, David E. Williams, Raymond J. Andersen,Veranja Karunaratne J.Nat. Sci.Foundation Sri Lanka 2014 42 (3):253-256

Research Communications: Abstracts and Conference Proceedings

1. Butanolides from the genus Hortonia Rukmal Ratnayake, Veranja Karunaratne, B.M. Ratnayake Bandara, Vijaya Kumar, Jhon. K.  MacLoed and Peta Simmonds. Asian Symposium   on Medicinal Plants, species and other Natural   Products.  Dhaka, Bangladesh, 2000, P. 127.

2. A Phytochemical approach to the classification of genus Hortonia in Sri Lanka.Rukmal Ratnayake, Veranja Karunaratne, Vijaya   Kumar, B.M. Ratnayake Bandara, Siril Wijesundara, Sunethra Dharmasena, Aruna   Wijesooriya, M.D. Dassanayake.Proc., Sri Lanka Assoc. Adv. Sci. 54, pp 291-292, 1998.

3. Two New Lactones from three Hortonia species. V. Karunaratne, R. Ratnayake, B.M. Ratnayake Bandara and Vijaya Kumar. Proc., Sri Lanka Assoc. Adv. Sci. 55, pp 232-233, 1999.

4. New bio active compounds from the genus Hortonia. Rukmal Ratnayake, Veranja Karunaratne, B.M.Ratnayake Bandara and Vijaya Kumar. Proc., Sri Lanka Assoc. Adv. Sci. 56, pp 244, 2000.

5. Biochemical and Taxonomical investigation of genus Hortonia in Sri Lanka. R. Ratnayake, V. Karunaratne, V. Kumar, R.M.R. Bandara, S. Wijesundara, A. Wijesooriya, M.D. Dassanayake. Proc. Ann. Res. Sessions, Faculty of Science, University of Peradeniya, Sri Lanka. 1998, p. 25.

6. Two New  Mosquitolarvicidal Compounds from Three Hortonia sp., R. Ratnayake, V. Karunaratne, B.M.R. Bandara and V. Kumar., Proc. University of Peradeniya Annual Research Sessions, 1999, p. 22.

7. Some Studies on the Genus Hortonia,  H.E.M.D.K.Ekanayake, R.M.R.P.Ratnayake and N.L.V.V.Karunaratne,Proc. University of Peradeniya Annual Research Sessions, 2002, p.146.

8. Four new butanolide derivatives from the genus Hortonia.Rukmal Ratnayake, B.M. Ratnayake Bandara, D. Siril A. Wijesundara and Veranja Karunaratne, Proc., Sri Lanka Assoc. Adv. Sci. 64, 2008

9. Differentiation of Hortonia ovalifolia and Hortonia floribunda by DNA barcoding. Prabasheeni Iddamalgoda, Sanath Rajapakse, Rukmal Ratnayake, B.M.Ratnayake Bandara, D.S. A. Wijesundara and Veranja Karunaratne, Proc., Sri Lanka Assoc. Adv. Sci. 64, 2008

10. Three new tetrahydroazulene derivatives and one new butenolide derivative from Hortonia, a genus endemic to Sri Lanka. R. Ratnayake, S. Jayasinghe, B. M. R. Bandara, D. S. A. Wijesundara, G. Carr, R. J. Anderson and V. Karunaratne. Proc. University of Peradeniya Annual Research Sessions, 2009, p. 245.

11. Hortonia angustifolia does not contain DPPH antioxidant alkaloids. Damith Perera, Rukmal Ratnayake, D. N. Karunaratne, B. M. Ratnayake Bandara, D. S. A. Wijesundara, and Veranja. Karunaratne. Proc. University of Peradeniya Annual Research Sessions, 2009, p. 254.

Ongoing Research:

Isolation of bioactive compounds from genes Hortonia.

Publications:

Books, Monographs and Book Chapters

1. Ratnayake, R.M.R.P., (2014). Petroleum Chemistry (CMU3232) Unit 4, The Open University of Sri Lanka, ISBN 978-955-23-1485-8 

2. Ranasinghe C., Ratnayake, R.M.R.P., (2013) Organic Chemistry CMF 2106 (Unit 2), The Open University of Sri Lanka, ISBN 978-955-23-1280-9 

Journal Articles

1. Ratnayake, R., Karunaratne, V., Bandara, B.M.R., Kumar, V., MacLeod, J.K. and Simmonds, P. 2001. Two new lactones with mosquito larvicidal activity from three Hortonia species, J. Nat. Prod, 64, 376-378. 

2. Ratnayake, R., Bandara, B.M. R., Wijesundara, D.S.A., Carr, G., Andersen, J. R., Karunaratne, V. 2008. Four new butanolide dervatives from Hortonia, a genus endemic to Sri Lanka, Journal of Chemical Research, 3, 134-136. 

3. Ratnayake, R., Bandara, B.M.R., Wijesundara, S., MacLeod, J.K., Simmonds, P. and Karunaratne, V. 2008. Bioactivity and chemistry of the genus Hortonia, Natural Products Research, 22(16), 1393-1402. 

4. Ratnayake, R., Jayasinghe, S.,Bandara, B.M.R., Andersen, R.J. and Karunaratne, V. 2008. Complete 2-D NMR assignment and antifungal activity of Ishwarane isolated from Hortonia a genus endemic to Sri Lanka, J. National Science Foundation of Sri Lanka, 36(1), 109-112. 

5. Carr, G., Williams, D.E., Ratnayake, R., Bandara, R., Wijesundara, S., Tarling, T., Balgi, A.D., Roberge, M., Andersen, R.J. and Karunaratne, V. 2012. Hortonones A to C Hydroazulenones from the genus Hortonia, Journal of Natural Products, 75(6), 1189–1191. 

6. Rajapakse, S., Iddamalgoda, P., Ratnayake, R., Wijesundara, D.S.A., Bandara, B.M.R. and Karunaratne, V. 2012. Evaluation of species limits of Hortonia by DNA barcoding, J. National Sci. Foundation Sri Lanka, 40(4), 345-349. 

7. Ratnayake, R., Perera, D., Karunaratne, D.N., Wijesundara, D.S.A., Carr, G., Williams, D.E., Andersen, R.J. and Karunaratne, V. 2014. Antioxidant activity and a new butanolide from the primitive endemic genus Hortonia, Journal of National Science Foundation 42(3), 279-282. 

8. Ratnayake, R. and Wickramaratne, N. 2017. A Novel Tetracyclic Sesquiterpene from the Genus Hortonia, Ceylon Journal of Science, 46 (3) 115-118. 

9. Ratnayake, R., Gunasekera, S., Williams, D., Andersen, R., and Karunaratne, V. 2019. A Novel Epoxy butenolides from the genus Hortonia, Ceylon Journal of Science, 48(1), 97-100. 

Abstracts and Conference Proceedings

1. Ratnayake, R., Karunaratne, V., Kumar, V., Bandara, B.M.R., Wijesundara, S., Dharmasiri, S., Weerasooriya, A. and Dassanayake, M.D. 1998. Biochemical and taxonomical investigation of genus Hortonia in Sri Lanka. Faculty of Science, University of Peradeniya, Annual Research Sessions, pp. 25. 

2. Ratnayake, R., Karunaratne, V., Kumar, V., Bandara, B.M.R., Wijesundara, S., Dharmesena, S., Weerasooriya, A. and Dassanayake, M.D. 1998. Phytochemical approach to the classification of genus Hortonia in Sri Lanka. Proc. Sri Lanka Assoc. Advmt. Sci., 54, pp. 291. 

3. Karunaratne, V., Ratnayake, R., Bandara, B.M.R. and Kumar, V. 1999. Two new lactones from three Hortonia species. Proc. Sri Lanka Assoc. Advmt. Sci., 55, pp. 232. 

4. Ratnayake, R., Karunaratne, V., Bandara, B.M.R. and Kumar, V. 1999. Two new mosquito larvicidal compounds from three Hortonia sp. Faculty of Science, University of Peradeniya Annual Research Sessions, pp. 22. 

5. Ratnayake, R., Karunaratne, V., Bandara, B.M.R. and Kumar, V. 2000. New bioactive compounds from the genus Hortonia. Proc. Sri Lanka Assoc. Advmt. Sci., 56, pp. 244. 

6. Karunaratne, V., Ratnayake, R., Bandara, B.M.R., Kumar, V., MacLoed, J. K. and Simmonds, P. 2000. Butanolides from the genus Hortonia, Asian Symposium on Medicinal Plants, Spices and other Natural Products X, Dhaka, Bangladesh, p. 127. 

7. Ekanayake, H.E.M.D.K., Ratnayake, R.M.R.P. and Karunaratne, N.L.V.V. 2002. Some studies on the genus Hortonia. Proc. University of Peradeniya Annual Research Sessions, pp. 146. 

8. Ratnayake, R., Bandara, B.M.R., Wijesundra, D.S.A. and Karunaratne, V. 2008. Four new butenolide derivatives from the genus Hortonia. Proc. 64th Annual Sessions, Sri Lanka Association for the Advancement of Science, pp. 155. 

9. Iddamalgoda, P., Rajapakse, S., Ratnayake, R., Bandara, B.M.R., Wijesundra, D.S.A. and Karunaratne, V. 2008. Differentiation of Hortonia ovalifolia and Hortonia floribunda by DNA barcoding. Proc. 64th Annual Sessions, Sri Lanka Association for the Advancement of Science, pp. 96. 

10. Perera, D., Ratnayake, R., Karunaratne, D.N., Ratnayake Bandara, B.M., Wijesundara D.S.A. and Karunaratne, V. 2009. Hortonia angustifolia does not contain DPPH sensitive antioxidant alkaloids. Proc. University of Peradeniya, Annual Research Sessions, 14, pp. 254-256. 

11. Ratnayake, R., Jayasinghe, S., Bandara, B.M.R., Wijesundara, D.S.A., Carr, G., Anderson, R.J. and Karunaratne, V. 2009. Three new tetrahydroazulene derivatives and one new butenolide derivative from Hortonia, a genus endemic to Sri Lanka. Proc. University of Peradeniya Annual Research Sessions, pp. 245. 

12. Gunasekera. M.R.S.S.B., Ratnayake, R.M.R.P. and Karunaratne, V. 2018. Novel Epoxy Butenolides from the Genus Hortonia. Asian Symposium on Medicinal Plants, Spices and other Natural Products XVI, Colombo, Sri Lanka, p. 138. 

13. Ratnayake, R., Karunaratne, V., Bandara, B.M.R. and Kumar, V. 2001. Two new lactones with mosquito larvicidal activity from three Hortonia species. Proc. Sri Lanka Association for the Advancement of Science, 57, pp. 376-377. 

 

 

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